But if you're looking for a good looking tote here's a way to do some good as well...
There are many lovely gifts in their online gift shop - so if the tote doesn't get you take a look at some of their other offerings: Hope Catalog
St. Jude, if you don't know, is a wonderful children's hospital and research center. So anything you buy on their site supports their important work.
Getting something good and doing something good - it doesn't get better than that!